Therapeutic Line : Factor-A® and Factor-A Plus®
Dramatic Skin Rejuvenation for the Visible Signs of Aging
Factor-A and Factor-A Plus are cutting-edge technologies that fall into the category known as Retinoids. Retinoids are a group of naturally occurring and synthetic compounds that have Vitamin A-like biological activity. They play a critical role in skin growth, repair and epithelial cell differentiation. Over the past 20 years, tremendous research has focused on certain Retinoids, particularly retinoic acid, for the purpose of treating various skin abnormalities including acne, actinic keratoses (pre-cancerous lesions) and skin changes due to photodamage and aging.
Jan Marini Skin Research has identified new stabilization and delivery components that enable Retinol, a dietary form of Vitamin A, to be delivered in a stable fashion where it is converted by certain enzymes into retinoic acid, while avoiding superficial redness, peeling and irritation. Some recent studies demonstrate that a stabilized Retinol may be more active in the skin than Retinoic acid at similar percentages.
Factor-A and Factor-A Plus contain the highest percentages of Retinol (all-trans-retinol). We have been able to provide this remarkable breakthrough by developing a proprietary, stabilized complex along with an unparalleled delivery system.
Summary of Benefits
- Retinoids protect against the appearance of ultraviolet radiation-induced aging skin changes
- Assists in decreasing or resolving the appearance of abnormal pigmentation (hyperpigmentation)
- Dramatic skin rejuvenation benefits in the visible signs of aging
- Noticeable reduction in the appearance of fine lines and wrinkles
- Skin appears smoother and more luminous
- Potent and effective tool for clearing and maintaining "problem skin"
Read about Retinol - A Potent Anti-aging Tool
For details on each product in this line, click on the product image bellow





Factor-A® Lotion
With Retinol

Improve the Appearance of Aging and Photo-Damaged Skin
Factor-A Lotion is a cutting edge technology that utilizes a form of Vitamin A called Retinol (all-trans-retinol/ROL). Numerous medical studies have confirmed that Retinol has similar activity and efficacy of Retinoic Acid (the active form of Vitamin A in Retin-A) without many of the side effects. Formulated for combination to oily skin types.
Jan Marini Skin Research has identified new stabilization and delivery components that enable Retinol to be delivered in a stable fashion where it is converted by certain enzymes into Retinoic acid, while avoiding superficial redness, peeling and irritation. Some recent studies demonstrate that stabilized Retinol may be more active in the skin than Retinoic acid. Dramatic improvement can be observed with regard to reversing the appearance of aging and photo-damaged skin. All trans Retinol is also a potent tool in treating the appearance of acneic skin and maintaining clearing.
1 oz. bottle
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Factor-A Plus® Lotion
With Retinol and Glycolic Acid
Accelerate Skin Resurfacing and Rejuvenation
Factor-A Plus Lotion combines the benefits of Retinol (all-trans-retinol/ROL) with the proven results of glycolic acid. This combination results in a synergistic formulation that accelerates skin resurfacing and skin rejuvenation as well as acting as an exceptional tool for clearing the appearance of acne-prone skin. Formulated for combination to oily skin types.
1 oz. bottle
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Factor-A® Cream
Emollient Base

Advanced Skin-enhancing Agents and Collagen Boosters
Factor-A Cream offers the same-cutting edge technology as Factor-A Lotion, formulated in a light emollient base. Advanced skin-enhancing agents and collagen boosters leave the skin feeling exceptionally silky, smooth and hydrated.
Factor-A Retinol Complex dramatically improves the appearance of aging and photodamaged skin, refines the skin's texture and promotes firmness and elasticity.
1 oz. jar
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Factor-A Plus® Cream
With Retinol and Glycolic Acid

Advanced Skin-enhancing Agents and Collagen Boosters in an Emollient Base
Factor-A Plus Cream offers the same cutting-edge technology as Factor-A Cream, combined with the proven benefits of glycolic acid. This combination results in a synergistic formulation that accelerates skin resurfacing and skin rejuvenation.
Factor-A Plus Cream's light emollient base contains advanced skin enhancing agents and collagen boosters that leaves skin feeling exceptionally silky, smooth and hydrated.
1 oz. jar
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Factor-A® Eyes For Dark Circles
With Vitamin K, Retinol, and Supporting Agents

Addresses Darkened Color, Lines, Wrinkles, and Other Signs of Aging Around the Eyes
Under-eye darkness can result from a combination of different factors. These factors can include:
- Thinner skin on the lower eyelids allowing pigment and vessels to be more visible.
- Gravity, which causes under-eyelid skin to move downward, initiating more stretching and thinning. This allows the blood vessels and pigment to become more noticeable.
- Cumulative sun exacerbates the skin-thinning, melanin content, and effects of gravity.
- Inflammation.
Jan Marini Skin Research Factor-A Eyes is a medically researched and tested formulation that dramatically addresses the combination of these contributing factors by utilizing Vitamin K, Retinol, and a number of supporting agents in a highly stabilized polymeric controlled release system.
Vitamin K has been shown in clinical studies to assist in decreasing the appearance of pigment and repairing blood vessels. Retinoids (such as stabilized retinol) have historically been proven to decrease the appearance of lines and wrinkles, reorganize collagen and assist in preventing the deposit of pigment in the epidermis.
The combination of these two ingredients directly addresses the appearance of darkened color, lines, wrinkles, and other signs of aging around the eyes. Users report rapid and noticeable improvement.
Factor-A Eyes for Dark Circles is packaged in 60 individually encapsulated and stabilized dosages. Used once daily in the evening, one capsule is used for both eyes. The gel-like, time-release formula is gently applied to the under eye area.
60 individually encapsulated dosages (2-month supply)
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Factor-A Plus® Mask
With Azaleic Acid, Salicylic Acid, Kojic Acid, All-Trans Retinol, and other Supporting Agents
Resurfaces and Clarifies Skin Texture, Fades Discoloration and Evens Skin Tone

Jan Marini Skin Research Factor-A Plus Mask is a potent resurfacing product that provides remarkable benefits. Our therapeutic mask contains a powerhouse blend of topical agents including Azaleic Acid, Salicylic Acid and Kojic Acid along with ALL-TRANS Retinol and a number of other effective supporting agents. Whether the goal is to dramatically improve skin texture, decrease the appearance of fine lines and wrinkles, resolve acne, address discoloration or to address a host of other common skin concerns, Factor-A Plus Mask provides exceptional results.
Factor-A Plus Mask brilliantly resurfaces and clarifies skin texture, fades the appearance of discoloration and evens skin tone, and assists in resolving acne, while helping to minimize the appearance of acne discoloration and scarring. Used once or twice a week, Factor-A Plus Mask dramatically improves the appearance of fine lines, wrinkles and sun damage. Facial skin is noticeably brighter, smoother, more refined and luminous.
2 oz. tube
8 oz. tube for Clinical/Professional use only
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Retinol
A Potent Anti-aging Tool
Retinoic acid has proven to be an extremely effective prescription medication, although in many cases the patient experiences mild to extreme redness and irritation. Because of the often difficult acclimation period and sometimes persistent continuing irritation, scientists have diligently searched for other Retinoids that would have equal or greater value without the potential side effects.
The most well known Retinoic acid compound is Retin-ATM which was approved by the FDA for the treatment of acne and later approved for the treatment of age-related skin changes due to cumulative photodamage.
Recently numerous university medical and research facilities have reported that Retinol (all-trans-retinol/ROL) has similar activity and efficacy of retinoic acid without the majority of the side effects associated with products such as Retin-ATM.
Medical research has proven that some Retinoids such as Retinol can reduce or reverse many of the visible signs of skin aging especially fine wrinkling and textural changes. New collagen deposition, greater proliferation of new blood vessels and capillary formation has been documented. Dramatic improvement can be observed with regard to skin smoothness, evening of skin tones and overall skin rejuvenation. Retinol also plays a prominent role in conditioning the skin prior to many cosmetic procedures such as facial surgery, CO2 laser resurfacing and chemical peels.
Retinol has proven to be a potent tool in treating acne by preventing the cells that line the follicular canal from sticking together and creating the solid impactions that block the follicle. This comedolytic action is unequalled in addressing the underlying mechanisms that contribute to acne.
Additionally when this new Retinol technology is formulated in combination with glycolic acid there is synergistic resurfacing enhancement.
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